The Canadian University Music Society will hold a special conference November 15, 2000 in Toronto as one of fifteen scholarly music societies participating in Toronto 2000: Musical Intersections. Graduate students whose papers are chosen for presentation in any session are eligible to compete for the George Proctor Prize, which is awarded for the best paper presented by a graduate student at the annual conference of the Canadian University Music Society. Those who wish to compete for the prize must submit four copies of their paper with the scholarly apparatus ; , exactly as it will be presented at the conference by September 1, 2000. From the submitted papers, a jury will select the finalists normally four ; , from which a winner will be chosen at the conference. In determining the winner, the jury will consider the presentation and the ability to handle questions from the audience as well as the quality of the paper. The amount of the award is $500 plus reimbursement at the same rate as that given to other student presenters for travel and accommodation expenses receipts are required ; . The winning paper will be considered for publication in the Canadian University Music Review and will be sent out to appraisers like other submissions. The jury reserves the right to withhold the award if, in its judgment, there are no suitable submissions. The competition is open to anyone who, at the time of submission of the abstract, is registered in a graduate degree program, does not yet hold a doctorate, does not hold a full-time teaching position, and is a member of CUMS. Previous winners are ineligible to compete. For more information contact: Dr. Alan Gillmor, 2000 CUMS Program Committee, Music Program, Carleton University, School for Studies in Art and Culture, 1125 Colonel By Drive, Ottawa, Ontario, K1S 5B6; or the CUMS President, Tom Gordon, Bishop's University tgordon ubishops . A bilingual society, our membership cuts across disciplinary boundaries, encompassing musicologists, theorists, composers, and performers. For further information on membership in CUMS SMUC, including details on past and future conferences and an application form, visit us at : upei ~cums.
The licensor's brand name and identity. Hikma enters into a licence either to manufacture a product, in which case the licensor customarily provides the API, or to market and distribute a finished product which Hikma purchases directly from the licensor. In Jordan, data exclusivity regulations mean that Hikma benefits from a five year period of market exclusivity from when its in-licensed originator pharmaceutical product is first registered, even if the product's patent in the applicable country of origin has expired or expires during the exclusivity period. This prevents other manufacturers from producing another generic or branded version of the in-licensed originator product for sale in Jordan and allows Hikma time to establish market share. Generally, in Saudi Arabia and Algeria any originator pharmaceutical product enjoys exclusivity until the originator pharmaceutical company's patents expire in the product's country of origin. Accordingly, Hikma also benefits from a period of exclusivity for its in-licensed products in the Gulf State markets, Saudi Arabia and Algeria for as long as the licensor's patent is valid in the product's country of origin. By entering into licensing or distribution agreements for originator pharmaceutical products, the Branded Pharmaceuticals business gains exclusive rights to patent protected drugs, whilst the economic return to the originator pharmaceutical company is included in the price paid by the Branded Pharmaceuticals business for either the API or the finished product under the relevant agreements. Hikma believes that in the future it may be required to pay a licensing fee in addition to purchasing the API from the originator pharmaceutical company. Typically, the licensing or distribution agreements have average terms of between five and ten years and are renewed automatically. The licensing agreements for several in-licensed products, including Prograf and Suuprax have, or soon will have, passed their initial ten-year terms and therefore have, or soon will become, subject to termination upon six months' notice. The Branded Pharmaceuticals business has generally been able to renegotiate prices or territories as appropriate during a contract's term and it is rare for licences or distribution agreements to be terminated. Some of the Branded Pharmaceuticals business's licence or distribution agreements do not specify minimum quantities of product to be purchased from the licensor, although this is a term in some of the contracts. Under the licence agreement for Prograf, however, Hikma must grant a royalty-free exclusive licence for improvements to Astellas Pharma. In the year ended 31 December 2004, the Branded Pharmaceuticals business had a total of 17 active licences from nine originator pharmaceutical companies, including Astellas Pharma, Tanabe Seiyaku, Daewoong, Edmond Pharma, Nycomed, Cheil Jedang, Sinclair, Helsinn and IBSA and one generic pharmaceutical company, Nicholas Piramal to register, distribute, sell and market, and in some cases, manufacture specified products. Hikma also sells one patent-protected originator pharmaceutical product under a promotion and distribution agreement with Eli Lilly. The terms of the promotion and distribution agreement with Eli Lilly are similar to the Branded Pharmaceuticals business's agreements for in-licensed products. Of the 17 active licences, eight are for products protected by patents or data exclusivity provisions in Algeria, Saudi Arabia or Jordan. Six active licences are from Astellas Pharma with whom Hikma entered into its first licence agreement in 1979. In April 2005, Fujisawa merged with Yamanouchi Pharmaceuticals and was renamed Astellas Pharma Inc. Hikma is not aware of any threats to its current licence agreements with Astellas Pharma but no assurance can be given that these agreements may not be modified or cancelled by Astellas Pharma in the future as a result of the merger or otherwise. In the year ended 31 December 2004, sales of pharmaceutical products under licence constituted approximately 10.9 per cent. of Hikma's net sales and 28.9 per cent. of the Branded Pharmaceuticals business's net sales. In the year ended 31 December 2004, sales of in-licensed products that benefit from data exclusivity or patent protection in the MENA Region constituted approximately 5.4 per cent. of Hikma's net sales and 15.6 per cent. of the Branded Pharmaceuticals business's net sales. Hikma expects the proportion of sales of its Branded Pharmaceuticals business represented by in-licensed products to remain at its current level in the next three years. Hikma's key markets for its Branded Pharmaceuticals business are Algeria, Saudi Arabia and Jordan. Details of the Branded Pharmaceuticals business's operations in these countries are set forth below. Key markets Algeria. Hikma's sales of branded pharmaceutical products in Algeria represented approximately 38.7 per cent. of the Branded Pharmaceuticals business's net sales in the year ended 31 December 2004 and 40.3 per cent. in the six months ended 30 June 2005. Based on IMS data, in the year ended 30 June 2005 Hikma was the second largest generic pharmaceutical company and fourth largest pharmaceutical company in Algeria with a market share of approximately 5.9 per cent. by sales value.56 Currently, the Branded Pharmaceuticals business sells 19 branded pharmaceutical products in 32 dosage strengths and forms in Algeria. Of these products, three are inlicensed from originator pharmaceutical companies and one is still patent protected. Of the Branded.
The company' s anti-infective product portfolio includes gram-positive antibiotic technology, gram-negative antibiotic technology, and broad-spectrum antibiotic technology targeted principally towards drug-resistant bacteria and hospital-acquired infections.
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By Scott Simmonds reprint permission ; A few months ago, we reviewed different insurance coverage issues for notfor-profits. Go to "Nonprofit Directors and Officers Insurance: The Good, the Bad, and the Ugly" and "Insurance Trips and Traps for Nonprofits" if you missed the first two installments. ; How about the administrative burden insurance causes an organization? Here are some tips for making your insurance program easier to manage. Have One Agent for All Your Coverage You'll have a better insurance program if one agent handles your entire insurance account. Using one agent will save you time and aggravation. You'll only have to make one call when you have a problem or a change in your operation. Having one agent also helps prevent gaps and overlaps in coverage. In the past, I've worked with several insurance buyers who thought that it was best to split the business up. Their idea was to let the two or three ; agents fight it out, scrapping for the business. I have never found that such arrangements work very well. Come claim time, it can be a nightmare when each insurer points to the other for coverage. If you currently have two agents, you know which one is the better service provider. Pick that agent and have him or her handle your entire insurance account. Have a Common Expiration Date for All Your Policies Having all your policies renew at the same time makes life simpler. All the issues are considered at one time. All the information is conveyed to your agent at the same time. There are fewer chances for misunderstandings and oversights. One cautionary note: If you have a workers' compensation policy with a premium over $5, 000, you probably have a rate factor called an experience modification, which adjusts your premium based on your losses compared to similar companies. I rarely recommend changing the dates of workers' compensation policies that have experience modifications. The new date can skew claims used in the calculation, increasing your costs. Talk with your insurance advisor before changing the date of your workers' compensation insurance policy. Review Your Coverage with Your Agent on a Regular Basis Meet with your insurance agent at least once a year to review your coverage, catch up on changes, and talk about hazards. The best time to do this is usually four months before your policy expires. Your agent should provide you with a summary of coverage and a listing of your losses. Talk about where your organization has been and where you plan to go in the near future. Are you considering mergers or acquisitions? Is a new product line being considered? New locations? New equipment? Are you discontinuing any operations? Let your agent be a part of your nonprofit. Let him or her know about risks you're concerned with. Look at your loss record. What can your agent do to help? Find out what services he or she offers that can assist with problem areas. Learn what services your insurer offers. Simplify the Administrative Process Whom do you call to change vehicles, add equipment, or check a driver's record? Have your insurance agent prepare a call sheet that outlines who does what for you. Some agencies have the salesperson handle all administrative issues. Other agencies have a team approach. Coverage concern contact--Whom do you call with a coverage question? Claims contact--You have an accident or fire; whom do you call? Policy change contact--You're adding a vehicle or changing your mailing address. Whom do you call? After-hours emergency contact--You have a fire on Sunday morning. Whom do you call? Alternate emergency contact--If the primary contact isn't available, whom do you call? Prevent Claims Accidents happen, but do they really need to? With training, thought, and analysis you can reduce and prevent accidents and claims. Having no accidents makes life easier for everyone! Review past incidents for clues as to what happened. Build a safety team to help identify hazards and offer solutions. Your employees should also be comfortable pointing out issues and making recommendations. Use your insurance company's loss-control experts. Look at all areas of potential losses: Property losses such as fire and windstorm Workers' compensation claims Product liability issues, including packaging and instruction sheets Prevention of slip-and-fall accidents by customers and employees Employment practices Intellectual property issues--unfair trade, violating patent or trademark.
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Focus on what is doable .107 Some examples of delivery of asthma education by clinicians during patient care visits table ; .108 References .109 Asthma and the School Child 113 The school asthma team . 114 Common asthma triggers in the school environment: . 114 What do school personnel need to know? . 115 Taking medications at school may be difficult 115 What can you do? . 116 Give the physical education teacher and or coach specific written instructions 116 Encourage parents to: . 117 Be aware of common school problems faced by the student with asthma: . 117 How Asthma-Friendly is Your School? handout ; . 118 School Asthma Management Plan form ; . 119 Resource Organizations for Patients and School Staff .121 References .122 Barriers to Care and Recommendations for Policy 125 What barriers to health care can affect children with asthma? .126 Barriers within the system include: .127 What can you do to overcome barriers to care? .127 References .128 Interventions 131 Interventions to improve health care for children with asthma .132 Considerations for interventions for children with asthma .133 Outcome measurements in children by major activity and age group table ; . 133 How can our health care system better serve children with asthma? .135 Suggestions for improving resource utilization .135 Suggestions for research .136 What can you do? .137 References .138 and vantin, for instance, ciprofloxacin.
C. Third Generation Cephalosporin: Cefotaxime Claforan ; , Ceftriaxone Rocephin ; , Ceftazidime Fortum ; and Cefixime Suprsx ; . D. Fourth Generation Cephalosporin: Cefipime Maxipime ; . 3. Carbepenems: This is a broad-spectrum agent. Such as: Imipenem Cilastatin Teinam ; and Meropenem Meronem ; . 4. Other Antimicrobial Groups: This includes the followings: A. Aminoglycosides: Such as, Amikin, Gen tamicin ; . B. Quinolones: Such as, Ciprobay ; . C. Macrolides: Such as, Erythromicin ; . D. Clindamicin.
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| Suprax 100Drug Name SPECTRACEF SUPRAX tazicef 1 gm add-vantage tazicef 1 gm piggyback vial tazicef 1 gm solr tazicef 1 gm vial TAZICEF 1 GM 50 BAG tazicef 2 gm add-vantage tazicef 2 gm solr tazicef 2 gm vial TAZICEF 2 GM 50 BAG tazicef 6 gm 100 ml vial tazidime tazidime w diluent VANTIN 100 MG TABLET VANTIN 100 MG 5 ML SUSPENSIO VANTIN 200 MG TABLET VANTIN 50 MG 5 SUSPENSION VELOSEF 250 MG CAPSULE VELOSEF 500 MG CAPSULE ZINACEF 1.5 GM ADD-VANT VIAL ZINACEF 1.5 GM VIAL zinacef 7.5 gm vial ZINACEF 750 MG ADD-VANT VIAL ZINACEF 750 MG INFUSION BTL ZINACEF D5W ZINACEF DEXTROSE 750 MG 50 M ZINACEF WATER 1.5 GM 50 ML CONTRACEPTIVES ALESSE-28 apri aranelle aviane BREVICON-28 camila cesia cryselle-28 CYCLESSA DEMULEN 1 35-28.
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The tear away feature has now been added to all vests inventoried at the Emergency Health Services Distribution Centre. This feature provides additional release points and more reflective markings. Ambulance Services choosing to do so, can order the new vests shown via normal ordering procedures. The Distribution Centre will offer a credit allowance towards multi purpose and site coordinator vests returned if they are still in good condition.
| Recombinant human GH rhGH; Nutropin ; and its placebo were generously provided by Genentech South San Francisco, CA ; and were administered under IND 34219. Salmon CT Calcimar ; , its placebo, and calcium carbonate CalEl D ; were the generous gifts of Rhone-Poulenc Rorer Pharmaceuticals Fort Washington, PA and cinnarizine.
Prescribed drugs, 2002, : rxlist top200 ; . Cells were harvested from cultures containing the highest concentration of each antibiotic that permitted growth, and plasmid was purified from those populations and transformed into E. coli strain DH5a-E. Because mutants exhibiting the highest level of antibiotic resistance come to dominate a population during growth in the presence of those antibiotics, it was necessary to sample only a small number of isolates from each re-transformed population to ensure that the most fit alleles had been recovered. A total of 140 isolates from the seven libraries were screened by the disk diffusion method, but none exhibited a greater level of aminoglycoside resistance than the wild-type clone. MICs were determined for a subset of 20 of those isolates and it was confirmed that none exhibited higher MICs for any of the drugs than did the wildtype clone. These results lead us to predict that the aac 6' ; -Iaa gene does not have the potential to evolve either increased activity toward either of its present substrates, amikacin, kanamycin and tobramycin, nor does it have the potential to evolve resistance toward gentamicin. Our confidence in that evolutionary prediction is based on the probability that we may have failed to detect an improved sequence by chance alone. m, the number of possible mutant genotypes containing n independent base substitution mutations, is, for instance, honda suprax 125.
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Viduals as they approach the service delivery system. Identified self advocates, who have faced these same hurdles, can help ease the transition for the consumer and the P&A. California utilizes consumers in many capacities, including participation in intra-agency work groups. The Arkansas P&A developed a volunteer system and an internet message board in 2004. The volunteer system seeks to develop a cadre of P&A volunteers who can serve as links between the agency and local communities throughout the state. These volunteers will help expand, amplify, and clarify community needs information coming into the PAIMI planning process. The message board uses internet technology to promote peer support and problem solving for parents with children receiving Special Education services, including services for children with mental illness. This model will be expanded into other disability, service and issue areas in coming years. To benefit consumers with mental illness in Maine, the P&A did a series of trainings for the state's human rights officers, many of whom had never received any such training. The trainings focused on the rights of individuals with mental illness and how these rights could be enforced. As a result, some of the officers have called the P&A for advice on how to handle various situations they have encountered in their duties. In Vermont, the P&A worked toward a collaborative model with staff from local mental health agencies to provide support for clients to speak with their own voices when they feel they have advocates available should they need greater expertise. Realizing that mental health services in the county were in a state of crisis, the Wisconsin P&A formed an alliance with other advocacy and consumer groups to develop the Milwaukee County Men.
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Detection rates for moderate and high-risk women and BRCA1 2 mutation carriers of 3.3 95% CI, 1.1-8.6 ; , 8.4 5.4-13.2 ; and 33 17-63 ; per 1, 000 person-years, respectively. The ratio of observed versus expected breast cancers in an age-matched average risk population was 2.7, 7.0 and 23.7, respectively. Results relating to tumour stage and sensitivity were less favourable in BRCA1 2 carriers and in women aged less than 40 years. The authors conclude that the results indicate the possibility of identifying young women at high risk for breast cancer. Goffin et al 2001 ; In a research letter, the authors describe a Canadian study which examined the sensitivity of mammography in a retrospective cohort of 161 Ashkenazi Jewish women diagnosed with invasive breast cancer aged less than 65 years, who were tested for BRCA1 2 mutations. Results found that breast cancers less than or equal to 2cm in size occurring in BRCA1 2 mutation carriers were statistically significantly less likely to be detectable than similar sized cancers in non-carriers 46% vs 89%; P 0.001 ; . The authors conclude that these results support the evidence that mammography is insensitive in detecting breast cancer in BRCA1 2 mutation carriers, and that alternative forms of early detection are likely to be beneficial in this high-risk group. Gui et al 2001 ; This UK data review of women with a family history of breast cancer aimed to select women for screening according to predicted risk, and to assess the value of annual CBE in addition to annual mammography. Women were divided into one group of 1, 500 women at standard risk lifetime risk less than 1: 6 ; and a second group of 1, 078 women at moderate high risk lifetime risk greater than or equal to 1: 6 ; cancers were detected, 12 in group I and 19 in group II; median age at diagnosis in group II was 45 years range 26-66 ; compared with 54.5 years range 38-63 ; in group I P 0.03 ; . Compared to breast cancer incidence in the normal population, standardised incidence ratio in group II was significantly higher at 2.8 95% CI, 1.7-4.2 the incidence ratio of women in group I was similar to that of the general population 1.1; 95% CI, 0.6-1.8 ; . 26 31 84% ; of cancers were palpable, of which 14 54% ; were not visible on mammography. Results support screening programmes for women with a family history of breast cancer, selected according to predicted risk, and justify screening from an earlier age than offered by the NHSBSP, with CBE in addition to mammography. Law et al 2001 ; Cancer detection rates and dose levels in the NHSBSP are used to compare numbers of cancers detected with numbers predicted to be induced by the screening process itself in this data analysis. Results showed that the numbers detected exceeded those induced by a large margin in women aged over 50 years. This margin was found to be reduced in younger women but remained positive to the age of 40 years. The authors also found that in younger women with a family history of breast cancer, the margin of benefit over risk was sufficient down to the age of 40 years, although they advise caution in annually screening women below the age of 35 years. Myles et al 2001 ; Early results are presented on the effectiveness of a UK mammography programme in 2, 998 women aged 19-71 with a moderate family history of breast cancer in terms of test and programme sensitivity and sojourn time. Results found that 50 breast cancers were diagnosed, with an observed incidence rate of 4.46 per 1, 000 person-years compared to an expected rate of 3.75 per 1, 000 personyears. Screen-detection rates at first and subsequent screenings were 5.00 and 4.93 per 1, 000, respectively, and interval cancer incidence in the first year following a negative screen was 0.91 per The classification and care of women at risk of familial breast cancer and clopidogrel.
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What are the potential risks and benefits of the medication and other treatment options? What are the anticipated side effects of the medication? How are the other elements of the treatment plan such as psychotherapy or school and family interventions ; integrated with the decision about medication? What can the provider do to help you get a good sense of what to look for, and who should be called with questions related to the medication or changes in behavior or symptoms? How will you, your child, and your doctor monitor progress, behavior changes, symptoms, and safety concerns? How can we best ensure that your child is actively involved in the discussion and decision-making related to the use of medications whenever possible ; ? Is there a clear communication plan for the family and the treating providers therapist and psychiatrist ; to ensure open lines of communication between all of them? How does any family history of mental disorders especially a history of bipolar disorder ; factor into the decision to use medication? How might you know when it is appropriate for your child to discontinue medication?, for example, cipro!
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REPRODUCTION AND TERATOLOGY 1. Fertility and general reproductive performance The effect of zopiclone was evaluated in three studies. First, treated male rats were mated with treated female rats, the oral doses of zopiclone being 0, 2, 12 and 120 mg kg. The males were treated for 10 weeks prior to mating, the females for 2 weeks prior to mating, during pregnancy and throughout a 3-week lactation period. In two further experiments, treated males 120 mg kg ; were mated with untreated females and untreated males were mated with treated females 120 mg kg ; . Both of the latter experimental conditions included a control group. Rate of pregnancy, number of implantations, rate of resorption and number of live fetuses were similar in control and low and medium dose-treated rats. However, mortality of pups was significantly higher in the mid dose group than in the control group. At the 120 mg kg dose, regardless whether treated males were mated with treated or untreated females, only ~10% of the females became pregnant and even in these animals resorption was complete. When high dose-treated females were mated with untreated males, the rate of pregnancy was only slightly lower than in controls 83% vs 100% ; and all pregnant females delivered live fetuses. Survival of fetuses, up to day 21 of lactation, was significantly lower than in controls. In conclusion, a 120 mg kg dose of zopiclone induces sterility in male animals, while in females it affects pregnancy rate only slightly. Up to 12 mg kg, the drug does not affect fertility and reproductive functions. 2. Teratology - rats The study was performed in groups of 20 rats each, given zopiclone orally at doses of 0, 5, 25 and 125 mg kg from day 5 to day 15 of gestation. In rats treated with the high dose of zopiclone, the following changes were seen when compared to the controls: food intake and final body weight day 20 ; were slightly but significantly lower, the rate of resorption was somewhat higher 9% vs 6% ; and the mean weight of live fetuses slightly but significantly lower 3.5 g vs 3.7 g ; . One pup had a sternal malformation, and five pups from the same mother had asymmetrical sternebrae. Both anomalies occur in the strain used. In conclusion, zopiclone is not teratogenic in rats in doses up to 125 mg kg.
But, it was brought up in class that sometimes the reasons for longer sentences for certain drugs is because of the violence that is associated with them.
It was originally approved under the accelerated approval regulations of subpart h of the food, drug, and cosmetic act.
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To prepare the rinse, add 1 2 tablespoon of dried goldenseal and 1 2 teaspoon of baking soda to 1 2 cup of warm water.
1. Pharmacia and Upjohn Inc. Camptosar. Product monograph. Feb 14, 2001. 2. Cancer Drug Manual 2001, Irinotecan Care Provider Monograph Vancouver, and B.C.: British Columbia Cancer Agency; 2001. : bccancer.bc accessed 2001 Dec 7 ; . 3. Gahart BL, Nazareno AR. eds. Intravenous medications: a handbook for nurses and other allied health personnel. 18th ed. St Louis; MO: Mosby Year Book; 2002: 570-6.
| Suprax gonorrhea treatmentThe test for Salmonella spp. in Folium Ginkgo should be negative. The maximum acceptable limits of other microorganisms are as follows 1214 ; . For preparation of decoction: aerobic bacteria--not more than 107 g; fungi--not 155.
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| An evidence-based rating system is provided for both safety and effectiveness. These ratings are based on criteria set forth by the Natural Medicines Comprehensive Database. A description of the criteria for these ratings is listed in tables 1 and 2. Using a grid approach, safety and effectiveness ratings are used to determine the overall recommendation as diagrammed in Chart 1. These criteria take into account only the scientific evidence available and do not take into account patient-specific factors; therefore, these recommendations serve only as a starting point for making decisions about patient care. "Consider recommending" means that there is enough evidence about safety and effectiveness to consider suggesting the product for patients who are interested. However, it is important to keep in mind that even though a product may fall into this category, it still may not be appropriate for certain patients due to disease state interactions, drug interactions, allergies, or other patient-specific factors.
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